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To enter the response of the aortic tissue into diabetogenic aggression, an aorta of a Psammomys that was fed HCD was eliminated and juxtaposed in the identical block as an aorta of an animal of the identical age fed with halophytes. The two aortas have been treated concurrently to review their histochemical characteristics, and then studied comparatively on the same section. This examination was repeated 9 instances to make sure reproducibility of measurements. The results are proven in Figure 2, boards four and 5. Some enzyme activities, such because the oxidoreductases, were particularly larger in the femoral and caudal arteries than in the aorta.
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In the healthy grownup rodents, enzyme actions had been very intense. They demonstrated that aortic myocytes are able to varied synthesis and catabolism processes. However, considering the frequency of atherosclerosis and its phenotypes, important variations appeared between the species studied. However, the most basic pathophysiological distinction is the low lipolytic energy of the aorta of Psammomys when compared to Wistar rats. This characteristic determines its atherosensitivity and makes this animal model extra applicable to the experimental development of atherosclerosis.